Clinical safety of induced CTL infusion through recombinant adeno-associated virus-transfected dendritic cell vaccination in Chinese cancer patients.

doi:10.1007/s12094-012-0854-7

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Clinical safety of induced CTL infusion through recombinant adeno-associated virus-transfected dendritic cell vaccination in Chinese cancer patients.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico - 1 Sept 2012

Di Lijun, Zhu Yulin, Jia Jun, Yu Jing, Song Gonghong, Zhang Jie, Che Li, Yang Huabing, Han Yan, Ma Bo, Zhang Chunrong, Yuan Yanhua, You Miaoning, Wan Fengling, Wang Xiaoli, Zhou Xinna, Ren Jun

Abstract excerpt

AIM: The aim of the study is to explore the safety of cytotoxic T lymphocytes (CTLs) infusion by transfected dendritic cells (DCs) with recombinant adeno-associated virus vector (rAAV) carrying CEA cDNA among advanced cancer patients. PATIENTS AND METHODS: A total of 27 cancer patients with tumor tissue expression positivity and/or sera-elevated level of CEA were subsequently divided into cohort A and B resulted...

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PMID: 22855148
DOI: 10.1007/s12094-012-0854-7

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