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Mitochondrial alteration in type 2 diabetes and obesity: An epigenetic link

12 Feb 2014

Abstract excerpt

The growing epidemic of type 2 diabetes mellitus (T2DM) and obesity is largely attributed to the current lifestyle of over-consumption and physical inactivity. As the primary platform controlling metabolic and energy homeostasis, mitochondria show aberrant changes in T2DM and obese subjects. While the underlying mechanism is under extensive investigation, epigenetic regulation is now emerging to play an important...

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PMID: 24552811
DOI: 10.4161/cc.28189

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