Article
Embryonic organoids recapitulate early heart organogenesis
2019-10-14
Abstract excerpt
Organoids are powerful models for studying tissue development, physiology, and disease. However, current culture systems disrupt the inductive tissue-tissue interactions needed for the complex morphogenetic processes of native organogenesis. Here we show that mouse embryonic stem cells (mESCs) can be coaxed to robustly undergo the fundamental steps of early heart organogenesis with an in vivo -like spatiotemporal...
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Identifiers and source
- Literature Corpus work
- 7526ec79-043f-5d30-a668-582a9ea926ef
- DOI
- 10.1101/802181