Article

HIGD2A is required for assembly of the COX3 module of human mitochondrial complex IV

2019-09-30

Abstract excerpt

Assembly factors play a critical role in the biogenesis of mitochondrial respiratory chain complexes I-IV where they assist in the membrane insertion of subunits, attachment of co-factors, and stabilization of assembly intermediates. The major fraction of complexes I, III and IV are present together in large molecular structures known as respiratory chain supercomplexes. A number of assembly factors have been prop...

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Literature Corpus work: 44b8c5af-0d5b-55fa-aa15-735398b6a2b2
DOI: 10.1101/787721

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