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Biosystem Analysis of the Hypoxia Inducible Domain Family Member 2A: Implications in Cancer Biology.

Genes - 18 Feb 2020

Salazar Celia, Yañez Osvaldo, Elorza Alvaro A, Cortes Natalie, García-Beltrán Olimpo, Tiznado William, Ruiz Lina María

Abstract excerpt

The expression of HIGD2A is dependent on oxygen levels, glucose concentration, and cell cycle progression. This gene encodes for protein HIG2A, found in mitochondria and the nucleus, promoting cell survival in hypoxic conditions. The genomic location of HIGD2A is in chromosome 5q35.2, where several chromosomal abnormalities are related to numerous cancers. The analysis of high definition expression profiles of...

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PMID: 32085461
DOI: 10.3390/genes11020206
PMCID: PMC7074167

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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