Back to search

Article

Dissecting the unique self-assembly landscape of the HIV-2 capsid protein

2025-09-12

Abstract excerpt

Human immunodeficiency virus type 2 (HIV-2) is a lentivirus closely related to HIV-1 but exhibits distinct molecular and clinical features that influence viral infectivity and efficacy of antiretroviral therapy. The HIV capsid is a critical structural component with multifaceted roles during infection and mediates some of the observed divergence between HIV-1 and HIV-2. Unlike HIV-1, study of the HIV-2 capsid is l...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
44ad7eef-22ba-522b-90a3-27fe4fa73eca
DOI
10.1101/2025.09.10.675445
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Dissecting the unique self-assembly landscape of the HIV-2 capsid proteinDOI 10.1101/2025.09.10.675445
Assembly properties of the human immunodeficiency virus type 1 CA protein.Semantic proximity
Determinants of the HIV-1 core assembly pathway.Semantic proximity
Supercharged Assembly: A Broad-Spectrum Mechanism of Action for Drugs that Undermine Controlled HIV-1 Viral Capsid FormationSemantic proximity
A trimer of dimers is the basic building block for human immunodeficiency virus-1 capsid assembly.Semantic proximity
HIV-1 capsid variability: viral exploitation and evasion of capsid-binding moleculesSemantic proximity
RNA-Mediated Virus Assembly: Mechanisms and Consequences for Viral Evolution and TherapySemantic proximity
How HIV-1 Gag assembles in cells: Putting together pieces of the puzzle.Semantic proximity
HIV-1 capsid: the multifaceted key player in HIV-1 infectionSemantic proximity
Interactions of HIV-1 Capsid with Host Factors and Their Implications for Developing Novel TherapeuticsSemantic proximity
The Ins and Outs of Herpesviral Capsids: Divergent Structures and Assembly Mechanisms across the Three SubfamiliesSemantic proximity
Multiple Roles of HIV-1 Capsid during the Virus Replication CycleSemantic proximity
The capsid protein of human immunodeficiency virus: interactions of HIV‐1 capsid with host protein factorsSemantic proximity
Select a neighboring publication to make it the new centre.