Article
Identification of additional body weight QTLs in the Berlin Fat Mouse BFMI861 lines using time series data.
Scientific reports - 14 Mar 2024
Delpero Manuel, Korkuć Paula, Arends Danny, Brockmann Gudrun A, Hesse Deike
Abstract excerpt
The Berlin Fat Mouse Inbred line (BFMI) is a model for obesity and metabolic syndrome. The sublines BFMI861-S1 and BFMI861-S2 differ in weight despite high genetic similarity and a shared obesity-related locus. This study focused on identifying additional body weight quantitative trait loci (QTLs) by analyzing weekly weight measurements in a male population of the advanced intercross line BFMI861-S1 x BFMI861-S2....
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