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Article

Diet-dependent genetic and genomic imprinting effects on obesity in mice.

Obesity (Silver Spring, Md.) - 1 Jan 2011

Cheverud James M, Lawson Heather A, Fawcett Gloria L, Wang Bing, Pletscher L Susan, R Fox Ashley, Maxwell Taylor J, Ehrich Thomas H, Kenney-Hunt Jane P, Wolf Jason B, Semenkovich Clay F

Abstract excerpt

Although the current obesity epidemic is of environmental origin, there is substantial genetic variation in individual response to an obesogenic environment. In this study, we perform a genome-wide scan for quantitative trait loci (QTLs) affecting obesity per se, or an obese response to a high-fat diet in mice from the LG/J by SM/J Advanced Intercross (AI) Line (Wustl:LG,SM-G16). A total of 1,002 animals from 78...

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Source

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Identifiers

PMID: 20539295
DOI: 10.1038/oby.2010.141
PMCID: PMC3677968

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Source receipt: pubmed, retrieved 7 Sept 2026.

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