Article

Arachidonic acid enhances TNF-α-induced tumorigenesis in human breast cancer cell line and rat mammary tumors.

2019-12-16

Abstract excerpt

<title>Abstract</title> <p>Background: Our group has previously reported that arachidonic acid (AA, 20:4n-6) levels are 10 times higher in rat mammary tumor tissue compared to the normal mammary gland. Nuclear factor kappaB (NF-κB) activation is often found to be constitutive in human breast cancer, showing higher activation in the more aggressive subtypes. Methods : We incubated the human breast cancer MCF-7 cel...

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Literature Corpus work: 4454b282-531a-54d1-9df2-8da8f9673261
DOI: 10.21203/rs.2.18909/v1

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