Article

Protective coinfection: influenza reprograms myeloid cells to limit CD8 T cell–mediated malaria pathology

2026-05-08

Abstract excerpt

<title>Abstract</title> <p>Malaria-associated acute lung injury (MA-ALI) is a life-threatening complication of malaria driven by pathogenic CD8 T cell responses with no effective pharmaceutical interventions. Here, we show that co-infection with non-lethal influenza/A/HKx31 (X31) protects mice from malarial pulmonary vascular leak and death. X31 co-infection drove the expansion of Ly6C+ monocyte-derived alveolar...

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Identifiers and source

Literature Corpus work: 443d9141-539b-5d42-b3d5-da1c22b36af1
DOI: 10.21203/rs.3.rs-9404453/v1

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