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A two-color haploid genetic screen identifies novel host factors involved in HIV latency

2021-01-22

Abstract excerpt

To identify novel host factors as putative targets to reverse HIV latency, we performed an insertional mutagenesis genetic screen in a latently HIV-1-infected pseudo-haploid KBM7 cell line (Hap-Lat). Following mutagenesis, insertions were mapped to the genome and bioinformatic analysis resulted in the identification of 69 candidate host genes involved in maintaining HIV-1 latency. A select set of candidate genes w...

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Literature Corpus work
43f2e531-29b5-5ade-8464-6a6692222555
DOI
10.1101/2021.01.20.427543
Open publication

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A two-color haploid genetic screen identifies novel host factors involved in HIV latencyDOI 10.1101/2021.01.20.427543
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