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Intravital imaging of <i>Candida albicans</i> identifies differential in vitro and in vivo filamentation phenotypes for transcription factor deletion mutants

2021-05-11

Abstract excerpt

Candida albicans is an important cause of human fungal infections. A widely studied virulence trait of C. albicans is its ability to undergo filamentation to hyphae and pseudohyphae. Although yeast, pseudohyphae and hyphae are present in pathological samples of infected mammalian tissue, it has been challenging to characterize the role of regulatory networks and specific genes during in vivo filamentation. In add...

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Literature Corpus work
43ba0629-4bca-5751-9b2e-a5e66ea5f23e
DOI
10.1101/2021.05.10.443530
Open publication

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Intravital imaging of <i>Candida albicans</i> identifies differential in vitro and in vivo filamentation phenotypes for transcription factor deletion mutantsDOI 10.1101/2021.05.10.443530
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