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Intravital imaging-based genetic screen reveals the transcriptional network governing Candida albicans filamentation during mammalian infection

27 Feb 2023

Abstract excerpt

Candida albicans is one of the most common human fungal pathogens. C. albicans pathogenesis is tightly linked to its ability to under a morphogenetic transition from typically budding yeast to filamentous forms of hyphae and pseudohyphae. Filamentous morphogenesis is the most intensively studied C. albicans virulence traits; however, nearly all of these studies have been based on in vitro induction of...

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PMID: 36847358
DOI: 10.7554/elife.85114

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