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Article

Regulation of filamentation in the human fungal pathogen <scp><i>C</i></scp><i>andida tropicalis</i>

15 Oct 2015

Abstract excerpt

The yeast-filament transition is essential for the virulence of a variety of fungi that are pathogenic to humans. N-acetylglucosamine (GlcNAc) is a potent inducer of filamentation in Candida albicans and thermally dimorphic fungi such as Histoplasma capsulatum and Blastomyces dermatitidis. However, GlcNAc suppresses rather than promotes filamentation in Candida tropicalis, a fungal species that is closely related...

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PMID: 26466925
DOI: 10.1111/mmi.13247

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