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Article

Use of In Vivo Imaging to Screen for Morphogenesis Phenotypes in Candida albicans Mutant Strains During Active Infection in a Mammalian Host.

Journal of visualized experiments : JoVE - 12 Oct 2022

Wakade Rohan S, Krysan Damian J, Wellington Melanie

Abstract excerpt

Candida albicans is an important human pathogen. Its ability to switch between morphologic forms is central to its pathogenesis; these morphologic changes are regulated by a complex signaling network controlled in response to environmental stimuli. These regulatory components have been highly studied, but almost all studies use a variety of in vitro stimuli to trigger filamentation. To determine how morphogenesis...

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PMID: 36314794
DOI: 10.3791/64258

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