Article

Model-based integration of genomics and metabolomics reveals SNP functionality in <i>Mycobacterium tuberculosis</i>

2019-02-20

Abstract excerpt

Human tuberculosis is caused by members of the Mycobacterium tuberculosis complex (MTBC) and presents variable disease outcomes. The variation has primarily been attributed to host and environmental factors, but recent evidence indicates an additional role of genetic diversity among MTBC clinical strains. Here, we used metabolomics to unravel the potential role of genetic variations in conferring strain-specific...

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Literature Corpus work: 4351ae17-1ad0-5e1d-ad0a-390ce658d396
DOI: 10.1101/555763

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