Article
In Silico Exploration of Mycobacterium tuberculosis Metabolic Networks Shows Host-Associated Convergent Fluxomic Phenotypes.
Biomolecules - 28 Feb 2022
Santamaria Guillem, Ruiz-Rodriguez Paula, Renau-Mínguez Chantal, Pinto Francisco R, Coscollá Mireia
Abstract excerpt
Mycobacterium tuberculosis, the causative agent of tuberculosis, is composed of several lineages characterized by a genome identity higher than 99%. Although the majority of the lineages are associated with humans, at least four lineages are adapted to other mammals, including different M. tuberculosis ecotypes. Host specificity is associated with higher virulence in its preferred host in ecotypes such as M....
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