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Article

Model-based integration of genomics and metabolomics reveals SNP functionality in Mycobacterium tuberculosis.

Proceedings of the National Academy of Sciences of the United States of America - 14 Apr 2020

Øyås Ove, Borrell Sonia, Trauner Andrej, Zimmermann Michael, Feldmann Julia, Liphardt Thomas, Gagneux Sebastien, Stelling Jörg, Sauer Uwe, Zampieri Mattia

Abstract excerpt

Human tuberculosis is caused by members of the Mycobacterium tuberculosis complex (MTBC) that vary in virulence and transmissibility. While genome-wide association studies have uncovered several mutations conferring drug resistance, much less is known about the factors underlying other bacterial phenotypes. Variation in the outcome of tuberculosis infection and diseases has been attributed primarily to patient...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32229570
DOI: 10.1073/pnas.1915551117
PMCID: PMC7165461

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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