Article
Systems-based approaches to probing metabolic variation within the Mycobacterium tuberculosis complex.
PloS one - 1 Jan 2013
Lofthouse Emma K, Wheeler Paul R, Beste Dany J V, Khatri Bhagwati L, Wu Huihai, Mendum Tom A, Kierzek Andrzej M, McFadden Johnjoe
Abstract excerpt
The Mycobacterium tuberculosis complex includes bovine and human strains of the tuberculosis bacillus, including Mycobacterium tuberculosis, Mycobacterium bovis and the Mycobacterium bovis BCG vaccine strain. M. bovis has evolved from a M. tuberculosis-like ancestor and is the ancestor of the BCG vaccine. The pathogens demonstrate distinct differences in virulence, host range and metabolism, but the role of...
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