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<i>In Vivo</i> Validation of Bimolecular Fluorescence Complementation (BiFC) to Investigate Aggregate Formation in Amyotrophic Lateral Sclerosis (ALS)

2020-10-09

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a form of motor neuron disease (MND) that is characterized by the progressive loss of motor neurons within the spinal cord, brainstem and motor cortex. Although ALS clinically manifests as a heterogeneous disease, with varying disease onset and survival, a unifying feature is the presence of ubiquitinated cytoplasmic protein inclusion aggregates containing TDP-43. However, th...

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Literature Corpus work
434df321-149b-50cc-9f10-dbf4d4fd1cf6
DOI
10.1101/2020.10.08.330894
Open publication

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<i>In Vivo</i> Validation of Bimolecular Fluorescence Complementation (BiFC) to Investigate Aggregate Formation in Amyotrophic Lateral Sclerosis (ALS)DOI 10.1101/2020.10.08.330894
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