Article

Discriminating Mild from Critical COVID-19 by Innate and Adaptive Immune Single-cell Profiling of Bronchoalveolar Lavages

2020-07-10

Abstract excerpt

<h4>ABSTRACT</h4> How innate and adaptive lung immune responses to SARS-CoV-2 synchronize during COVID-19 pneumonitis and regulate disease severity is poorly established. To address this, we applied single-cell profiling to bronchoalveolar lavages from 44 patients with mild or critical COVID-19 versus non-COVID-19 pneumonia as control. Viral RNA-tracking delineated the infection phenotype to epithelial cells, bu...

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Literature Corpus work: eaa5a590-45f7-5459-ba71-d1117c9f687b
DOI: 10.1101/2020.07.09.196519

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