Article

Type I interferon-dependent IFIT3 signaling is critical for viral clearance in airway neutrophils

2023-03-21

Abstract excerpt

<title>Abstract</title> <p>Neutrophilic inflammation characterizes several respiratory viral infections including COVID-19-related ARDS, although its contribution to disease pathogenesis remains poorly understood. Here, we identified two neutrophil subpopulations (A1 and A2) in the airway compartment of 52 severe COVID-19 subjects, where loss of the A2 subset correlated with increased viral burden and reduced 30-...

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Literature Corpus work: 5ac74e88-f3a0-5da0-994e-d5f01fbe1c42
DOI: 10.21203/rs.3.rs-1812836/v1

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