Article

A Tethered Ligand Assay to Probe SARS-CoV-2:ACE2 Interactions

2021-08-09

Abstract excerpt

<h4>ABSTRACT</h4> SARS-CoV-2 infections are initiated by attachment of the receptor-binding domain (RBD) on the viral Spike protein to angiotensin-converting enzyme-2 (ACE2) on human host cells. This critical first step occurs in dynamic environments, where external forces act on the binding partners and multivalent interactions play critical roles, creating an urgent need for assays that can quantitate SARS-CoV-...

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Literature Corpus work: 43390126-9728-5949-849e-348f5215a0b7
DOI: 10.1101/2021.08.08.455468

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