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Single-Molecule Investigation of the Binding Interface Stability of SARS-CoV-2 Variants with ACE2

8 Mar 2024

Abstract excerpt

The SARS-CoV-2 pandemic spurred numerous research endeavors to comprehend the virus and mitigate its global severity. Understanding the binding interface between the virus and human receptors is pivotal to these efforts and paramount to curbing infection and transmission. Here we employ atomic force microscopy and steered molecular dynamics simulation to explore SARS-CoV-2 receptor binding domain (RBD) variants...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38644967
DOI: 10.1021/acsnanoscienceau.3c00060

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