Article

A Tethered Ligand Assay to Probe the SARS-CoV-2 ACE2 Interaction under Constant Force

2020-09-28

Abstract excerpt

<h4>ABSTRACT</h4> The current COVID-19 pandemic has a devastating global impact and is caused by the SARS-CoV-2 virus. SARS-CoV-2 attaches to human host cells through interaction of its receptor binding domain (RBD) located on the viral Spike (S) glycoprotein with angiotensin converting enzyme-2 (ACE2) on the surface of host cells. RBD binding to ACE2 is a critical first step in SARS-CoV-2 infection. Viral attach...

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Literature Corpus work: 4fcd38d1-48aa-56f0-bc49-f1e28e8bde91
DOI: 10.1101/2020.09.27.315796

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