Article

SARS-COV-2 induced Diarrhea is inflammatory, Ca <sup>2+</sup> Dependent and involves activation of calcium activated Cl channels

2021-04-28

Abstract excerpt

<h4>ABSTRACT</h4> Diarrhea occurs in 2-50% of cases of COVID-19 (∼8% is average across series). The diarrhea does not appear to account for the disease mortality and its contribution to the morbidity has not been defined, even though it is a component of Long Covid or post-infectious aspects of the disease. Even less is known about the pathophysiologic mechanism of the diarrhea. To begin to understand the pathoph...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 432ca16f-76e1-5f60-99aa-3c614c87b868
DOI: 10.1101/2021.04.27.441695

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

SARS-COV-2 induced Diarrhea is inflammatory, Ca <sup>2+</sup> Dependent and involves activation of calcium activated Cl channelsDOI 10.1101/2021.04.27.441695Read

SARS-CoV-2 Productively Infects Human Gut EnterocytesSemantic proximity Read

Single-cell analyses reveal SARS-CoV-2 interference with intrinsic immune response in the human gutSemantic proximity Read

Human Rotavirus Diarrhea Is Associated with Altered Trafficking and Expression of Apical Membrane Transport ProteinsSemantic proximity Read

Relative Abundance of SARS-CoV-2 Entry Genes in the Enterocytes of the Lower Gastrointestinal TractSemantic proximity Read

Inflammation in the COVID-19 airway is due to inhibition of CFTR signaling by the SARS-CoV-2 Spike proteinSemantic proximity Read

Inflammation in the COVID-19 airway is due to inhibition of CFTR signaling by the SARS-CoV-2 spike proteinSemantic proximity Read

Control of CDH1/E-Cadherin Gene Expression and Release of a Soluble Form of E-Cadherin in SARS-CoV-2 Infected Caco-2 Intestinal Cells: Physiopathological Consequences for the Intestinal Forms of COVID-19Semantic proximity Read

Modeling SARS-CoV-2 infection <i>in vitro</i> with a human intestine-on-chip deviceSemantic proximity Read

Mechanical force sensing drives extrusion of Enterovirus A71-infected cells from colonic epithelial organoidsSemantic proximity Read

Robust and persistent SARS-CoV-2 infection in the human intestinal brush border expressing cellsSemantic proximity Read

CLIC and membrane wound repair pathways enable pandemic norovirus entry and infectionSemantic proximity Read

Variable susceptibility of intestinal organoid-derived monolayers to SARS-CoV-2 infectionSemantic proximity Read