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Article

Epigenetic memory at malaria virulence genes

5 Jan 2007

Abstract excerpt

During its red blood cell stage, the malaria parasite Plasmodium falciparum can switch its variant surface proteins (P. falciparum erythrocyte membrane protein 1) to evade the host immune response. The var gene family encodes P. falciparum erythrocyte membrane protein 1, different versions of which have unique binding specificities to various human endothelial surface molecules. Individual parasites each contain...

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PMID: 17209011
DOI: 10.1073/pnas.0609084103

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