Article

The molecular basis of coordinated antigen switching enabling chronic infection by human malaria parasites

2025-07-16

Abstract excerpt

The exceptional virulence of the human malaria parasite, Plasmodium falciparum , is in large part attributed to the adhesive properties of infected red blood cells and the parasite’s ability to avoid antibody recognition through antigenic variation. Both properties are derived from a hypervariable protein placed on the infected cell surface called PfEMP1, different versions of which are encoded by members of the...

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Literature Corpus work: 390f249c-8c74-5cd2-8b3d-6205b1174b88
DOI: 10.1101/2025.07.16.665170

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