Article

Identification of single nucleotide variants using position-specific error estimation in deep sequencing data

2018-11-23

Abstract excerpt

<h4>Background</h4> Targeted deep sequencing is a highly effective technology to identify known and novel single nucleotide variants (SNVs) with many applications in translational medicine, disease monitoring and cancer profiling. However, identification of SNVs using deep sequencing data is a challenging computational problem as different sequencing artifacts limit the analytical sensitivity of SNV detection, es...

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Literature Corpus work: 429a721a-b518-52aa-ae50-08f8d142d664
DOI: 10.1101/475947

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