Article

Osmolar modulation drives reversible cell cycle exit and human pluripotent cell differentiation via NF-κВ and WNT signaling

2023-04-14

Abstract excerpt

<h4>ABSTRACT</h4> Terminally differentiated cells are regarded as the most stable and common cell state in adult organisms as they reside in growth arrest and carry out their cellular function. Improving our understanding of the mechanisms involved in promoting cell cycle exit would facilitate our ability to manipulate pluripotent cells into mature tissues for both pharmacological and therapeutic use. Here, we de...

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Literature Corpus work: 428fc004-1c4b-5f2c-bd1c-5f9819c70948
DOI: 10.1101/2023.04.14.536882

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