Article
Phenotypic and molecular characterization of proliferating and differentiated GnRH-expressing GnV-3 cells.
Molecular and cellular endocrinology - 30 Jan 2011
Mansuy Virginie, Geller Sarah, Rey Jean-Pierre, Campagne Céline, Boccard Julien, Poulain Pierre, Prevot Vincent, Pralong François P
Abstract excerpt
GnRH neurons provide the primary driving force upon the neuroendocrine reproductive axis. Here we used GnV-3 cells, a model of conditionally immortalized GnRH-expressing neurons, to perform an analysis of cell cycle and compare the gene expression profile of proliferating cells with differentiated cells. In the proliferation medium, 45 ± 1.5% of GnV-3 cells are in S-phase by FACS analysis. In the differentiation...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.