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Article

Osmotic niche changes as multifaceted trigger of cellular regenerative processes in organ injury

2025-09-12

Abstract excerpt

<h4>Summary</h4> Cell niches are organ-specific and characterized by a variety of distinct biophysical cues, including mechanics and osmolality. Injury disrupts this cellular environment and marks the start of regenerative processes. It remains unclear whether bone fracture alters the osmolality of bone marrow, and how associated changes in the extracellular matrix (ECM) affect marrow-resident cells in the onset...

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Literature Corpus work
2f22b189-b507-5470-b253-c2f6c3e74880
DOI
10.1101/2025.09.07.674644
Open publication

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Osmotic niche changes as multifaceted trigger of cellular regenerative processes in organ injuryDOI 10.1101/2025.09.07.674644
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