Article

ROS signaling-induced mitochondrial Sgk1 regulates epithelial cell plasticity

2022-12-23

Abstract excerpt

Many types of differentiated cells can reenter the cell cycle upon injury or stress. The mechanisms underlying this cell plasticity are still poorly understood. Here we investigated cell plasticity regulation using a zebrafish model, in which a population of differentiated epithelial cells are reactivated under a physiological context. We observed a robust and sustained increase in mitochondrial membrane potential...

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Literature Corpus work: 31d3132a-7c6c-5e69-8a05-20fd97ff9eba
DOI: 10.1101/2022.12.23.521432

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