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Article

Sarcoidosis activates diverse transcriptional programs in bronchoalveolar lavage cells

26 Jul 2016

Abstract excerpt

BACKGROUND: Sarcoidosis is a multisystem immuno-inflammatory disorder of unknown etiology that most commonly involves the lungs. We hypothesized that an unbiased approach to identify pathways activated in bronchoalveolar lavage (BAL) cells can shed light on the pathogenesis of this complex disease. METHODS: We recruited 15 patients with various stages of sarcoidosis and 12 healthy controls. All subjects underwent...

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PMID: 27460362
DOI: 10.1186/s12931-016-0411-y

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