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Co-immunization with pre-erythrocytic antigens alongside circumsporozoite protein can enhance sterile protection against Plasmodium sporozoite infection.

2022-07-19

Abstract excerpt

<title>Abstract</title> <p>Malaria-causing <italic>Plasmodium</italic> parasites have a complex life cycle and present numerous antigen targets that may contribute to protective immune responses. The currently recommended vaccine—RTS,S—functions by targeting the <italic>P. falciparum</italic> circumsporozoite protein (CSP), which is the most abundant surface protein of the sporozoite form responsible for initiati...

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Literature Corpus work
42687c50-52e9-5af5-9c2a-2aff533f83fa
DOI
10.21203/rs.3.rs-1781959/v1
Open publication

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Co-immunization with pre-erythrocytic antigens alongside circumsporozoite protein can enhance sterile protection against Plasmodium sporozoite infection.DOI 10.21203/rs.3.rs-1781959/v1
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