Article

Multi-functional antibodies are induced by the RTS,S malaria vaccine and associated with protection in a phase I/IIa trial

2019-11-22

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> RTS,S is the leading malaria vaccine candidate, but only confers partial efficacy against malaria in children. RTS,S is based on the major Plasmodium falciparum sporozoite surface antigen, circumsporozoite protein (CSP). The induction of anti-CSP antibodies is important for protection, however, it is unclear how protective antibodies function. <h4>Methods</h4> We quantifi...

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Literature Corpus work: 5f7e77dc-6529-5c4b-87a8-0a46137a74a0
DOI: 10.1101/851725

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