Article

Low immunogenicity of malaria pre-erythrocytic stages can be overcome by vaccination

2020-09-04

Abstract excerpt

<h4>ABSTRACT</h4> Vaccine discovery and development critically depends on predictive assays, which prioritise protective antigens. Immunogenicity is considered one important criterion for progression of candidate vaccines to further clinical evaluation, including phase I/II trials. Here, we tested this assumption in an infection and vaccination model for malaria pre-erythrocytic stages. We engineered Plasmodium...

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Literature Corpus work: ea2db905-9ba7-5fd3-bd2b-cc9caa1a7a41
DOI: 10.1101/2020.09.03.281238

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