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PixR, a novel activator of conjugative transfer of IncX4 resistance plasmids, mitigates the fitness cost of <i>mcr-1</i> carriage in <i>Escherichia coli</i>

2021-08-06

Abstract excerpt

<h4>ABSTRACT</h4> The emergence of the plasmid-borne colistin resistance gene mcr-1 threats public health. IncX4-type plasmids are one of the most epidemiologically successful vehicles for spreading mcr-1 worldwide. Since MCR-1 is known for imposing a fitness cost to its host bacterium, the successful spread of mcr-1 -bearing plasmids might be linked to high conjugation frequency, which would enhance the maint...

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Literature Corpus work
5892fd82-4016-59cf-98c7-6dc968eb6227
DOI
10.1101/2021.08.04.455183
Open publication

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PixR, a novel activator of conjugative transfer of IncX4 resistance plasmids, mitigates the fitness cost of <i>mcr-1</i> carriage in <i>Escherichia coli</i>DOI 10.1101/2021.08.04.455183
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