Article

Transcriptomic perspective on acromegaly- related PIT-1/SF-1 positive pituitary tumors

2025-05-30

Abstract excerpt

Neuroendocrine pituitary tumors (PitNETs) are classified based on clinical manifestation and expression of pituitary cell lineage-specific transcription factors (TFs) and hormones. A subtype of acromegaly-related tumors was found to express PIT-1 and SF-1 TFs, two markers of distinct pituitary cells. They were considered as multilineage or “somatogonadotoph” tumors. The aim of our study was to determine their iden...

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Literature Corpus work: f2cf6656-2d1a-5512-a87c-dac4ed599338
DOI: 10.1101/2025.05.28.656330

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