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Article

Alpha-synuclein dysfunction in Lewy body diseases.

Movement disorders : official journal of the Movement Disorder Society - 1 Aug 2005

Tofaris George K, Spillantini Maria Grazia

Abstract excerpt

alpha-Synuclein belongs to a small group of natively unfolded proteins that can transiently bind to lipid membranes and acquire a partial alpha-helical conformation. Its relevance to Parkinson's disease (PD) is based on mutations found in familial cases of the disease and its presence in filament...

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PMID: 16092089
DOI: 10.1002/mds.20538

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16092089-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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