Article

Hiding in the yolk: a unique feature of <i>Legionella pneumophila</i> infection of zebrafish

2021-10-19

Abstract excerpt

The zebrafish has become a powerful model organism to study host-pathogen interactions. Here, we developed a zebrafish model of Legionella pneumophila infection to dissect innate immune responses. We show that L. pneumophila cause zebrafish larvae death in a dose dependent manner, and that macrophages are the first line of defence, with neutrophils cooperating to clear the infection. When either macrophages or n...

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Literature Corpus work: 421d564e-6bbb-5104-8e92-c3b8cdb5c3a1
DOI: 10.1101/2021.10.18.464513

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