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Article

Innate Immune Response to Streptococcus iniae Infection in Zebrafish Larvae

23 Oct 2012

Abstract excerpt

Streptococcus iniae causes systemic infection characterized by meningitis and sepsis. Here, we report a larval zebrafish model of S. iniae infection. Injection of wild-type S. iniae into the otic vesicle induced a lethal infection by 24 h postinfection. In contrast, an S. iniae mutant deficient in polysaccharide capsule (cpsA mutant) was not lethal, with greater than 90% survival at 24 h postinfection. Live...

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PMID: 23090960
DOI: 10.1128/iai.00642-12

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