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A novel vertebrate model of <i>Staphylococcus aureus</i> infection reveals phagocyte-dependent resistance of zebrafish to non-host specialized pathogens

18 Aug 2008

Abstract excerpt

With the emergence of multiply resistant Staphylococcus aureus, there is an urgent need to better understand the molecular determinants of S. aureus pathogenesis. A model of staphylococcal pathogenesis in zebrafish embryos has been established, in which host phagocytes are able to mount an effective immune response, preventing overwhelming infection from small inocula. Myeloid cell depletion, by pu.1...

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PMID: 18715285
DOI: 10.1111/j.1462-5822.2008.01213.x

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