Article

In vitro culture of aberrant basal-like cells from fibrotic lung tissue

2020-08-17

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Rationale</h4> In idiopathic pulmonary fibrosis (IPF) atypical epithelial cells are present in the alveolar compartment. Their origin and contribution to IPF pathogenesis is unknown. We recently cultured a distinct population of cells, which readily grew from fibrotic lung tissue, but only rarely from non-fibrotic tissue. Here we aimed to characterize these fibrosis-enriched cells and deter...

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Literature Corpus work: ed3cf065-a46e-504d-96f7-a2c0ab5dc51e
DOI: 10.1101/2020.08.16.247866

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