Article

Ubiquitous overexpression of CXCL12 confers radiation protection and enhances mobilization of hematopoietic stem and progenitor cells

2020-01-09

Abstract excerpt

<h4>ABSTRACT</h4> C-X-C Motif Chemokine Ligand 12 (CXCL12; aka SDF1α) is a major regulator of a number of cellular systems, including hematopoiesis where it influences hematopoietic cell trafficking, proliferation, and survival during homeostasis and upon stress and disease. A variety of constitutive, temporal, ubiquitous and cell-specific loss-of-function models have documented the functional consequences on hem...

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Literature Corpus work: 41cef31c-4da7-5f26-b2c0-091b26d8a61e
DOI: 10.1101/2020.01.08.899427

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