Article

Partial Inhibition of Viral Replication Machinery Enhances Recombination in Herpes Simplex Viruses

2025-09-15

Abstract excerpt

Herpes simplex viruses (HSV-1 and HSV-2) are widespread human pathogens, most commonly causing oral and genital lesions. These DNA viruses use recombination as a major driver of evolution. Intragenomic and intergenomic recombination events can be detected both in vivo and in vitro. As viral recombination is tightly linked to replication, deciphering mechanisms that specifically effect recombination remains a chall...

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Literature Corpus work: 4152ad0f-d035-5340-aa5c-e113aa38cc78
DOI: 10.1101/2025.09.15.676234

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