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Ancient Recombination Events between Human Herpes Simplex Viruses.

Molecular biology and evolution - 1 Jul 2017

Burrel Sonia, Boutolleau David, Ryu Diane, Agut Henri, Merkel Kevin, Leendertz Fabian H, Calvignac-Spencer Sébastien

Abstract excerpt

Herpes simplex viruses 1 and 2 (HSV-1 and HSV-2) are seen as close relatives but also unambiguously considered as evolutionary independent units. Here, we sequenced the genomes of 18 HSV-2 isolates characterized by divergent UL30 gene sequences to further elucidate the evolutionary history of this virus. Surprisingly, genome-wide recombination analyses showed that all HSV-2 genomes sequenced to date contain HSV-1...

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Identifiers

PMID: 28369565
DOI: 10.1093/molbev/msx113
PMCID: PMC5455963

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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