Article

Age-related trajectories of DNA methylation network markers: a parenclitic network approach to a family-based cohort of patients with Down Syndrome

2020-03-12

Abstract excerpt

Despite the fact that the cause of Down Syndrome (DS) is well established, the underlying molecular mechanisms that contribute to the syndrome and the phenotype of accelerated aging remain largely unknown. DNA methylation profiles are largely altered in DS, but it remains unclear how different methylation regions and probes are structured into a network of interactions. We develop and generalize the Parenclitic Ne...

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Literature Corpus work: 41438f9f-bc3e-54d6-b23e-78cfe45ece1c
DOI: 10.1101/2020.03.10.986505

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Age-related trajectories of DNA methylation network markers: a parenclitic network approach to a family-based cohort of patients with Down SyndromeDOI 10.1101/2020.03.10.986505Read

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