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DNA Methylation Alterations in Blood Cells of Toddlers with Down Syndrome

23 Jul 2021

Abstract excerpt

Recent research has provided evidence on genome-wide alterations in DNA methylation patterns due to trisomy 21, which have been detected in various tissues of individuals with Down syndrome (DS) across different developmental stages. Here, we report new data on the systematic genome-wide DNA methylation perturbations in blood cells of individuals with DS from a previously understudied age group-young children. We...

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PMID: 34440289
DOI: 10.3390/genes12081115

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