Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Accelerated epigenetic aging in newborns with Down syndrome

6 Jun 2022

Abstract excerpt

Accelerated aging is a hallmark of Down syndrome (DS), with adults experiencing early-onset Alzheimer's disease and premature aging of the skin, hair, and immune and endocrine systems. Accelerated epigenetic aging has been found in the blood and brain tissue of adults with DS but when premature aging in DS begins remains unknown. We investigated whether accelerated aging in DS is already detectable in blood at...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Down syndrome and intellectual disability research
Share to Epigenetics and DNA Methylation
Share to Prenatal Screening and Diagnostics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35661546
DOI: 10.1111/acel.13652

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Accelerated epigenetic aging in newborns with Down syndromePMID 35661546Read ↗

Accelerated epigenetic aging in Down syndromeSemantic proximity Read ↗

DNA Methylation Alterations in Blood Cells of Toddlers with Down SyndromeSemantic proximity Read ↗

Identification of a DNA methylation signature in blood cells from persons with Down SyndromeSemantic proximity Read ↗

Atypical aging in Down syndrome.Semantic proximity Read ↗

Recent advances in the understanding of transient abnormal myelopoiesis in Down syndromeSemantic proximity Read ↗

Epigenomic signature of major congenital heart defects in newborns with Down syndromeSemantic proximity Read ↗

Epigenetic Clock Analysis in Children With Fetal Alcohol Spectrum DisorderSemantic proximity Read ↗

Clinical significance of preleukemic somatic GATA1 mutations in children with Down syndromeSemantic proximity Read ↗

The natural history of transient abnormal myelopoiesis in neonates and children with Down syndromeSemantic proximity Read ↗

Epigenomic signature of major congenital heart defects in newborns with Down syndromeSemantic proximity Read ↗

Low-Pass Whole Genome Bisulfite Sequencing of Neonatal Dried Blood Spots Identifies a Role for RUNX1 in Down Syndrome DNA Methylation ProfilesSemantic proximity Read ↗

Characterizing epigenetic aging in an adult sickle cell disease cohortSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.